PL-SAX for Biomolecules
and temperature range, essential for oligonucleotide purification and analysis. With PL-SAX for Biomolecules, separations using denaturing conditions of temperature, organic solvent, and high pH are all possible.
PL-SAX for Biomolecules delivers improved chromatography for self-complementary or G-rich sequences that may associate to form aggregates or hairpin structures. The 5 μm material provides high-efficiency separations of n and n-1 sequences, with 8 μm, 10 μm, and 30 μm particles available for rapid scale-up.
- Oligonucleotide Analysis
Product Details
- Small particles deliver excellent chromatographic performance
- Wide range of particle sizes for flexible oligonucleotide analysis and scale-up purification
- Exceptional stability for long column lifetime
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Oligonucleotide Virtual Lab
Explore proven methods and resources to help advance analysis for the broad range of oligonucleotide workflows.
Videos
- Key Literature
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Optimizing Separation of Oligonucleotides with Anion-Exchange Chromatography
This application note describes common method parameters that can be optimized when purifying oligonucleotides ranging from 25 to 100 bases in length.
- Application Notes
- English
- 11 Apr 2022
- 416.32 KB
Oligonucleotide Purification Solutions - Agilent PLRP-S and PL-SAX HPLC Columns
Polymeric particles, such as PLRP-S and PL-SAX, are ideal for analyzing and purifying oligonucleotides. Because these materials are thermally and chemically stable, they enable diverse techniques.
- Brochures
- English
- 20 Oct 2023
- 4.15 MB
Oligonucleotide Purification using Anion Exchange Liquid Chromatography
Easily find all you need for oligonucleotide purification using anion exchange liquid chromatography with this workflow ordering guide.
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- English
- 23 Apr 2024
- 623.89 KB
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Agilent Wins Multiple 2022 Scientists' Choice Awards
Agilent received two 2022 Scientists’ Choice Awards for Drug Discovery & Development, Virtual Event of the Year and Innovative Content of the Year, at the SLAS2022 International Conference & Exhibition on February 7th, 2022. The Scientists’ Choice Awards recognize the world’s most innovative and effective analytical science technologies and communications.
- Agilent Wins Multiple 2022 Scientists' Choice Awards
- 15 Feb 2022