Columns and Standards for Oligonucleotide HPLC Analysis
AdvanceBio oligonucleotide HPLC columns offer the robustness necessary for successful HPLC oligonucleotide analysis at high pH. AdvanceBio columns have high resolving power and are robust enough to withstand challenging conditions to successfully separate trityl-off, deprotected oligonucleotides,
AdvanceBio Spin Columns address the need for efficient sample preparation of proteins or oligonucleotides under aqueous conditions, preserving native structure with suitable ionic strength and pH. Users can easily and quickly remove excess salts or undesired small molecules from their sample matrix or exchange the sample matrix between different buffer conditions. These gel-filtration-based spin columns are available in analytical and semipreparative scale columns for single samples, as well as 96-sample plates for high-throughput settings.
Agilent received two 2022 Scientists’ Choice Awards for Drug Discovery & Development, Virtual Event of the Year and Innovative Content of the Year, at the SLAS2022 International Conference & Exhibition on February 7th, 2022. The Scientists’ Choice Awards recognize the world’s most innovative and effective analytical science technologies and communications.
Professor Michael Butler, head of the National Institute for Bioprocessing Research and Training (NIBRT) Cell Technology Group (CTG), explains that the characterisation and analysis of glycans is important for the biopharma sector as it can help in the development of therapeutic agents, such as monoclonal antibodies and other recombinant proteins. These are used in therapies in a range of serious conditions including cancer, inflammatory diseases, and cardiovascular diseases. The mechanism of action depends upon their strong affinity to molecular targets associated with disease.